In addition to traditional angiographic and intravascular ultrasound core analysis, Cardialysis is an innovative leader in the field, continually researching new and emerging imaging modalities. Such an approach ensures that the evaluation of a particular device/drug will be carried out using cutting edge technology whilst maximising the information gained from a clinical study. Closely guided by clinical experts in the specific field, Cardialysis serves as a Core Laboratory for a variety of these imaging techniques.
A recent successful example of implementing a novel intra-vascular imaging research technique is with optical coherence tomography (OCT). OCT is a light-based imaging modality permitting the in-vivo visualisation of biologic tissues with an unmatched resolution of 15 microns. This unique capability has resulted in OCT being rapidly adopted and accepted in stent studies with the ability to provide accurate assessment of both stent apposition and tissue coverage over individual stent struts. Other exciting applications include the detailed assessment of the vessel wall and its structural changes over time together with the characterisation of atherosclerotic plaque components.
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8. Prati F, Regar E, Mintz G, Arbustini E, Di Mario C, Jang IK, Akasaka T, Costa M, Guagliumi G, Grube E, Ozaki Y, Pinto F and Serruys PW for the Expert’s document . Expert review on methodology, terminology and clinical applications of optical coherence tomography. Physical principles, methodology of image acquisition and clinical application for assessment of coronary arteries and atherosclerosis. Eur Heart J. 2010 Feb;31(4):401-15.
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