Prof. Dr. Nicolas M. van Mieghem

Imaging of cardiac valves

Dr. Nicolas M. Van Mieghem obtained his medical degree and cardiology degree at the Catholic University of Leuven, Belgium. After subsequent Fellowships in interventional cardiology in Ziekenhuis Oost-Limburg Genk, Belgium, Lenox Hill Hospital, New York, USA and Erasmus Medical Center, Rotterdam, the Netherlands, he joined the department of interventional cardiology in the Thoraxcenter, Erasmus MC as a senior staff member in February 2010. He is the clinical director of interventional cardiology since 2014. He became full professor of interventional cardiology in September 2019...

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He is involved in the percutaneous coronary interventions program and has a particular focus on transcatheter heart valve interventions. He obtained the degree of PhD based upon his research in transcatheter valve therapies. So far he has published and co-authored over 200 scientific papers in peer-reviewed journals. Dr. Van Mieghem is principle investigator and steering committee member in multiple ongoing international trials evaluating various transcatheter valve technologies, mechanical circulatory support platforms and coronary atherectomy devices. He is a Fellow of the European Society of Cardiology (FESC) and the American College of Cardiology.



Dr. Joost Daemen

Coronary angiography

Dr. Joost Daemen, MD, PhD obtained his degree in medicine at the Erasmus University Medical Center, Rotterdam in 2005 and did 2 years of internal medicine training and 4 years of general cardiology training at the Thoraxcenter, Rotterdam. Dr. Daemen is expecting to finish his interventional...

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...cardiology training, for which he spent several months at the Insel University Medical Center Bern Switzerland, in early 2015. In 2008, he obtained his PhD degree with cum laude as a result of dedicated research in the field of interventional cardiology with specific interest in long-term follow-up, safety and efficacy of drug-eluting stents and stent thrombosis, resulting in co-authorship in over 75 peer reviewed publications. Specific attention went to high-risk patient subsets, cost-effectiveness, comparative effectiveness of PCI versus CABG and quality-of-life analyses. Dr. Daemen is actively involved in several drug-eluting stent trials and is Principal Investigator of 4 trials focusing on the safety and efficacy of renal sympathetic denervation in hypertension, heart failure, vasospastic angina and heart failure. Dr. Daemen is a member of the editorial board of EuroIntervention and the Netherlands Heart Journal, member of Young ICIN, and has completed courses in biomedical statistics and device training.



Dr. Claire Ben Ren


Dr. Claire Ben Ren MD, PhD, is an imaging physician specialized in echocardiography in structural heart disease. She works in the interventional cardiology department of the Thoraxcenter, Erasmus Medical Center, since October 2014. Dr. Ren is mainly involved in echocardiography imaging in patients undergoing transcatheter heart valve interventions. She also joined Cardialysis in 2014 and is the Supervisor of the Echo Core Lab.

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Dr. Ren graduated from West China School of Medicine, Chengdu, China in 2010. During her research master, she focused on 3D echocardiography on aortic valve annulus quantification, while completing training on transthoracic and transoesophageal echocardiography in the Cardiology Department of the West China Hospital. In 2014 she obtained the PhD diploma in Cardiology at the Thoraxcenter, Erasmus Medical Center. Her PhD topic was 3D echocardiography for left ventricular function, mitral regurgitation and left atrial function. She has published and co-authored over 45 articles in peer reviewed journals.



Dr. Ernest Spitzer

Non-invasive techniques

Dr. Ernest Spitzer is a consultant cardiologist with focus on non-invasive cardiovascular imaging and interventional cardiology. He joined Cardialysis in 2014 were is involved in the design of randomized clinical trials, supervision of the non-invasive imaging Core Lab, and supervision of the Clinical Events Committee. Dr. Spitzer started a PhD program at Erasmus University Medical Center in 2016 on invasive and non-invasive cardiovascular imaging, concomitant heart failure and valvular heart disease, and interventions.

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Dr. Spitzer graduated in 2004 with Summa Cum Laude from the Catholic University of Saint Mary, Arequipa, Peru. He completed his cardiology training at the University Hospital Miguel Servet, Zaragoza, Spain, followed by a training in advanced cardiac imaging at the General Hospital of Vienna, Austria. In 2013, he was awarded a research fellowship by the European Association of Percutaneous Cardiovascular Interventions of the European Society of Cardiology and by the Spanish Society of Cardiology, with which Dr. Spitzer completed a clinical research fellowship at Bern University Hospital, Switzerland. In addition, he completed a 4-year master program in statistics and research methodology at the Autonomous University of Barcelona and started a PhD pogram at the Erasmus University Medical Center in 2016 focused on invasive and non-invasive cardiovascular imaging, concomitant heart failure and valvular heart disease, and interventions. He has contributed with 50+ articles in peer-reviewed journals. Dr. Spitzer joined Cardialysis in November 2014.



Dr. Sing-Chien Yap

ECG & Electrophysiology

Sing-Chien Yap, MD, PhD, FEHRA, is a cardiologist-electrophysiologist at the Erasmus MC, Rotterdam, the Netherlands. His clinical activities include catheter ablations of arrhythmias (including Stereotaxis), CIED implantations and lead extractions. In addition, he is responsible for the inherited arrhythmias outpatient clinic. He is an EHRA certified cardiac device and electrophysiology specialist.


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He obtained his medical degree from the University of Utrecht in 2004. He was granted a MD Clinical Research Trainee Grant from the NWO for his PhD research. After obtaining his PhD degree in 2007, he completed a research fellowship (2009-2010) at the Division of Cardiac Electrophysiology, University Health Network, Toronto, Canada. His research in Canada was focused on catheter ablation of adults with congenital heart disease. He completed his training in cardiology and his clinical fellowship in cardiac electrophysiology at the Department of Cardiology, Erasmus MC.
He has authored over 50 original articles in peer-reviewed journals. His main research topics are sudden cardiac death, ICD therapy and congenital heart disease. Currently, he focuses his research on early detection and treatment of ventricular arrhythmias in high-risk populations. He is a Fellow of the European Heart Rhythm Association (FEHRA) and active member of the Netherlands Heart Rhythm Association (NHRA).



Dr. Rohit Bhagwandien

Electrophysiology and Cardiac Implantable Electronic Devices

Dr. Rohit Bhagwandien, MD, obtained his degree in medicine at the Erasmus University Medical Center, Rotterdam in 2004 and did 2 years of internal medicine training and 4 years of general cardiology training at the Thoraxcenter, Rotterdam. After finishing his cardiology training he started his fellowship electrophysiology. 


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He is a staff member in the Thoraxcenter since 2010. He is actively involved in patient care, education, and cardiovascular research. He is currently Principal Investigator in several device and ablation trails. His focus is on atrial fibrillation, anticoagulation, and cardiac implantable electronic devices, including re-synchronization therapy, ICD’s, subcutaneous ICD’s, and leadless pacemakers. He has written several articles in peer-reviewed journals.