Core lab literature references


  1. Serruys PW, Foley DP, de Feyter PJ, eds. Quantitative coronary angiography in clinical practice. Dordrecht, the Netherlands: Kluwer Academic, 1994
  2. Ramcharitar S, Onuma Y, Aben JP, Consten C, Weijers B, Morel MA, Serruys PW. A novel dedicated quantitative coronary analysis methodology for bifurcation lesions. EuroInterv.2008;3:553-557
  3. Onuma Y, Girasis C, Aben JP, Sarno G, Piazza N, Lokkerbol C, Morel MA, Serruys PW. A novel dedicated 3-dimensional quantitative coronary analysis methodology for bifurcation lesions. EuroIntervention. 2011 Sep;7(5):629-35
  4. Computer-assisted myocardial blush quantification after percutaneous coronary angioplasty for acute myocardial infarction: a substudy from the TAPAS tria. Vogelzang M, Vlaar PJ, Svilaas T, Amo D, Nijsten MWN, Zijlstral F. European Heart Journal 2009; 30, 594–599.
  5. Georgios Sianos, Marie-Angèle Morel, Arie Pieter Kappetein, Marie-Claude Morice, Antonio Colombo,Keith Dawkins, Marcel van den Brand, Nic Van Dyck, Mary E Russell, Friedrich W. Mohr, Patrick W Serruys. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease EuroIntervention 2005; 1: 219-227
  6. Garg S, Sarno G, Girasis C, Vranckx P, de Vries T, Swart M, Bressers M, Garcia-Garcia HM, van Es GA, Räber L, Campo G, Valgimigli M, Dawkins KD, Windecker S, Serruys PW. Patient-level pooled analysis assessing the impact of the SYNTAX (synergy between percutaneous coronary intervention with taxus and cardiac surgery) score on 1-year clinical outcomes in 6,508 patients enrolled in contemporary coronary stent trials. JACC Cardiovasc Interv. 2011 Jun;4(6):645-53.
  7. Stella-Lida Papadopoulou, Chrysafios Girasis, Anoeshka Dharampal, Vasim Farooq, Yoshinobu Onuma, Alexia Rossi, Marie-Angèle Morel, Gabriel Krestin, Patrick W. Serruys, Pim De Feyter. The Multislice Computed Tomography (MSCT) SYNTAX Score: a feasibility and reproducibility study. 2012 JACC: Cardiovascular Imaging.
  8. A clinical protocol for analysis of the structural integrity of the Medtronic CoreValve System® frame and its application in patients with 1-year minimum follow-up. Piazza N, Grube E, Gerckens U, Schuler G, Linke A, den Heijer P, Kovacs J, Spyt T, Laborde JC, Morel MA, Nuis RJ, Garcia-Garcia HM, de Jaegere P, Serruys PW. EuroIntervention 2010 Jan;5(6):680-6.
  9. Abdelghani M, Miyazaki Y, de Boer ES, Aben JP, van Sloun M, Suchecki T, van 't Veer M, Soliman O, Onuma Y, de Winter R, Tonino PAL, van de Vosse FN, Rutten MCM, Serruys PW. Videodensitometric quantification of paravalvular regurgitation of a transcatheter aortic valve: in vitro validation. EuroIntervention 2018;13(13):1527-1535.
  10. Miyazaki Y, Abdelghani M, de Boer ES, Aben JP, van Sloun M, Suchecki T, van 't Veer M, Collet C, Asano T, Katagiri Y, Tenekecioglu E, Soliman OII, Onuma Y, de Winter R, Tonino P, van de Vosse FN, Rutten MCM, Serruys PW. A novel synchronised diastolic injection method to reduce contrast volume during aortography for aortic regurgitation assessment: in vitro experiment of a transcatheter heart valve model. EuroIntervention 2017;13(11):1288-1295.
  11. Miyazaki Y, Soliman OII, Abdelghani M, Katsikis A, Naz C, Lopes S, Warnack B, Cox M, Onuma Y, Serruys PW. Acute performance of a novel restorative transcatheter aortic valve: preclinical results. EuroIntervention 2017;13(12):e1410-e1417.
  12. Abdelghani M, Tateishi H, Miyazaki Y, Cavalcante R, Soliman OII, Tijssen JG, de Winter RJ, Baan J, Jr., Onuma Y, Campos CM, Leite RS, Mangione JA, Abizaid A, Lemos PA, de Brito FS, Jr., Serruys PW. Angiographic assessment of aortic regurgitation by video-densitometry in the setting of TAVI: Echocardiographic and clinical correlates. Catheter Cardiovasc Interv 2017;90(4):650-659.
  13. Abdel-Wahab M, Abdelghani M, Miyazaki Y, Holy EW, Merten C, Zachow D, Tonino P, Rutten MCM, van de Vosse FN, Morel MA, Onuma Y, Serruys PW, Richardt G, Soliman OI. A Novel Angiographic Quantification of Aortic Regurgitation After TAVR Provides an Accurate Estimation of Regurgitation Fraction Derived From Cardiac Magnetic Resonance Imaging. JACC Cardiovascular interventions 2018;11(3):287-297.
  14. Tateishi H, Campos CM, Abdelghani M, Leite RS, Mangione JA, Bary L, Soliman OI, Spitzer E, Perin MA, Onuma Y, Serruys PW, Lemos PA, Brito FS, Jr. Video densitometric assessment of aortic regurgitation after transcatheter aortic valve implantation: results from the Brazilian TAVI registry. EuroIntervention 2016;11(12):1409-18.
  15. Tateishi H, Abdelghani M, Cavalcante R, Miyazaki Y, Campos CM, Collet C, Slots TLB, Leite RS, Mangione JA, Abizaid A, Soliman OII, Spitzer E, Onuma Y, Serruys PW, Lemos PA, de Brito FS, Jr. The interaction of de novo and pre-existing aortic regurgitation after TAVI: insights from a new quantitative aortographic technique. EuroIntervention 2017;13(1):60-68.


Intra Coronary Imaging

  1. Serruys PW, Garcia-Garcia HM, Buszman P, Erne P, Verheye S, Aschermann M, et al. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation. 2008 Sep 9;118(11):1172-82.
  2. Gerstein HC, Ratner RE, Cannon CP, Serruys PW, Garcia-Garcia HM, van Es GA, et al. Effect of rosiglitazone on progression of coronary atherosclerosis in patients with type 2 diabetes mellitus and coronary artery disease: the assessment on the prevention of progression by rosiglitazone on atherosclerosis in diabetes patients with cardiovascular history trial. Circulation. 2010 Mar 16;121(10):1176-87.
  3. Serruys PW, Morice MC, Kappetein AP, Colombo A, Holmes DR, Mack MJ, et al. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med. 2009 Mar 5;360(10):961-72.
  4. Tanabe K, Serruys PW, Degertekin M, Grube E, Guagliumi G, Urbaszek W, et al. Incomplete stent apposition after implantation of paclitaxel-eluting stents or bare metal stents: insights from the randomized TAXUS II trial. Circulation. 2005 Feb 22;111(7):900-5.
  5. Garcia-Garcia HM, Mintz GS, Lerman A, Vince DG, Margolis MP, van Es GA, et al. Tissue characterisation using intravascular radiofrequency data analysis: recommendations for acquisition, analysis, interpretation and reporting. EuroIntervention. 2009 Jun;5(2):177-89.
  6. Garg S, Serruys PW, van der Ent M, Schultz C, Mastik F, van Soest G, et al. First use in patients of a combined near infra-red spectroscopy and intra-vascular ultrasound catheter to identify composition and structure of coronary plaque. Eurointervention. 2010 Jan;5(6):755-6.
  7. Regar E vLA, Serruys PW. Optical coherence tomography in cardiovascular research. London: Informa Healthcare. 2007;ISBN 1841846112.
  8. Gonzalo N, Garcia-Garcia HM, Serruys PW, Commissaris KH, Bezerra H, Gobbens P, et al. Reproducibility of quantitative optical coherence tomography for stent analysis. EuroIntervention. 2009 Jun;5(2):224-32.
  9. Farooq V, Gogas BD, Okamura T, Heo JH, Magro M, Gomez-Lara J, et al. Three-dimensional optical frequency domain imaging in conventional percutaneous coronary intervention: the potential for clinical application. Eur Heart J. 2011 Nov 21. 
  10. Okamura T, Onuma Y, Garcia-Garcia HM, Bruining N, Serruys PW. High-speed intracoronary optical frequency domain imaging: implications for three-dimensional reconstruction and quantitative analysis. Eurointervention. 2012 Feb;7(10):1216-26.


Magnetic Resonance Imaging

  1. van Geuns, RJ, Baks, T, Gronenschild, EHBM et al. Automatic quantitative left ventricular analysis of cine MR images by using three-dimensional information for contour detection. Radiology 2006; 240, 1: 215-21
  2. Baks, T, Cademartiri, F, Moelker, AD, Weustink, AC, van Geuns, RJ, Mollet, NR et al. Multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction. J Am Coll Cardiol 2006; 48, 1: 144-52



  1. Brouwer IA, Zock PL, Camm AJ, Böcker D, Hauwer RNW, Wever EFD, Dullemeijer C, Ronden JE, Kata MB, Lubinski A, Buschler H, Schouten EG for the SOFA Study Group. Effect of fish oil on ventricular tachyarrhythmia and death in patiens with implantable cardioverter defibrillators. JAMA 2006;295:2613-2619.
  2. Kimman GJ, Theuns DA, Janse PA, Rivero-Ayerza M, Scholten MF, Szili-Torok T, Jordaens LJ. One-year follow-up in a prospective, randomized study comparing radiofrequency and cryoablation of arrhythmias in Koch’s triangle; clinical symptoms and event recording. Europace 2006;8:592-5.
  3. Janse PA, Van Belle YL, Theuns DAMJ, Rivero-Ayerz M, Scholten MF, Jordaens LJ. Symptoms versus objective rhythm monitoring in patiens with paroxysmal atrial fibrillation undergoing pulmonary vein isolation. Eur J Cardiovasc Nurs 2008;7 (2): 147-151.
  4. Theuns DAMJ, Jordaens LJ. Remote monitoring in implantable defibrillator therapy. Neth Heart J 2008;16:53-56.
  5. Jordaens L. Electrocardiography core laboratory. Cardialysis 2008.
  6. Caliskan K, Ujvari B, Bauernfeind T, Theuns DAMJ, VAN Domburg RT, Akca F, Jordaens L, Simoons ML, Szili-Torok T. The prevalence of early repolarization in patients with noncompaction cardiomyopathy presenting with malignant ventricular arrhythmias. J Cardiovasc Electrophysiol 2012 May 15. doi:10.1111/j.1540-8167.2012.02325.x.
  7. van der Boon RM, Nuis RJ, Van Mieghem NM, Jordaens L, Rodés-Cabau J, van Domburg RT, Serruys PW, Anderson RH, de Jaegere PP. New conduction abnormalities after TAVI-frequency and causes. Nat Rev Cardiol. 2012 ;9:454-63.
  8. Valk SD, Dabiri-Abkenari L, Theuns DA, Thornton AS, Res JC, Jordaens L. Ventricular fibrillation and life-threatening ventricular tachycardia in the setting of outflow tract arrhythmias - The place of ICD therapy. Int J Cardiol. 2012. 



  1. Lang, R.M., Badano, L.P., Tsang, W., Adams, D.H., Agricola, E., Buck, T., Faletra, F.F., Franke, A., Hung, J., Pérez De Isla, L., Kamp, O., Kasprzak, J.D., Lancellotti, P., Marwick, T.H., McCulloch, M.L., Monaghan, M.J., Nihoyannopoulos, P., Pandian, N.G., Pellikka, P.A., Pepi, M., Roberson, D.A., Shernan, S.K., Shirali, G.S., Sugeng, L., Ten Cate, F.J., Vannan, M.A., Zamorano, J.L., Zoghbi, W.A. EAE/ASE recommendations for image acquisition and display using three-dimensional echocardiography. (2012) Journal of the American Society of Echocardiography, 25 (1), pp. 3-46.
  2. Soliman, O.I.I., Krenning, B.J., Geleijnse, M.L., Nemes, A., Van Geuns, R.-J., Baks, T., Anwar, A.M., Galema, T.W., Vletter, W.B., Cate, F.J.T. A comparison between QLAB and tomtec full volume reconstruction for real time three-dimensional echocardiographic quantification of left ventricular volumes. (2007) Echocardiography, 24 (9), pp. 967-974.
  3. Soliman, O.I.I., Kirschbaum, S.W., van Dalen, B.M., van der Zwaan, H.B., Delavary, B.M., Vletter, W.B., van Geuns, R.-J.M., Ten Cate, F.J., Geleijnse, M.L. Accuracy and Reproducibility of Quantitation of Left Ventricular Function by Real-Time Three-Dimensional Echocardiography Versus Cardiac Magnetic Resonance (2008) American Journal of Cardiology, 102 (6), pp. 778-783.
  4. Anwar, A.M., Soliman, O.I.I., Geleijnse, M.L., Nemes, A., Vletter, W.B., ten Cate, F.J. Assessment of left atrial volume and function by real-time three-dimensional echocardiography (2008) International Journal of Cardiology, 123 (2), pp. 155-161.
  5. Anwar, A.M., Geleijnse, M.L., Soliman, O.I.I., McGhie, J.S., Frowijn, R., Nemes, A., Bosch, A.E., Galema, T.W., ten Cate, F.J. Assessment of normal tricuspid valve anatomy in adults by real-time three-dimensional echocardiography (2007) International Journal of Cardiovascular Imaging, 23 (6), pp. 717-724.
  6. De Jaegere, P.P., Piazza, N., Galema, T.W., Otten, A., Soliman, O.I., Van Dalen, B.M., Geleijnse, M.L., Kappetein, A.P., Garcia, H.M., Van Es, G.A., Serruys, P.W. Early echocardiographic evaluation following percutaneous implantation with the self-expanding CoreValve Revalving System aortic valve bioprosthesis. (2008) EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 4 (3), pp. 351-357.
  7. Akin S., Soliman O.I., Constantinescu A.A., Akca F., Birim O., van Domburg R.T., Manintveld O., Caliskan K.. Haemolysis as a first sign of thromboembolic event and acute pump thrombosis in patients with the continuous-flow left ventricular assist device HeartMate II. Neth Heart J (2016) 24:134–142
  8. McGhie J.S., Menting M.E., Vletter W.B., Frowijn R., Roos-Hesselink J.W., Soliman O.I., van der Zwaan H.B., Geleijnse M.L., van den Bosch A.E.. A Novel 13-Segment Standardized Model for Assessment of Right Ventricular Function Using Two-Dimensional iRotate Echocardiography. Echocardiography. 2015 Nov 2. doi: 10.1111/echo.13102. [Epub ahead of print]
  9. Abdelghani M., Onuma Y., Zeng Y., Soliman O.I., Ma J., Huo Y., Guidotti A., Nietlispach F., Maisano F., Serruys P.W.. The Sino Medical AccuFit transcatheter mitral valve implantation system. EuroIntervention. 2015 Sep;11 Suppl W:W84-5. doi: 10.4244/EIJV11SWA26
  10. Di Martino L.F., Vletter W.B., Ren B., Schultz C., Van Mieghem N.M., Soliman O.I., Di Biase M., de Jaegere P.P., Geleijnse M.L.. Prediction of paravalvular leakage after transcatheter aortic valve implantation. Int J Cardiovasc Imaging. 2015 Oct;31(7):1461-8. doi: 10.1007/s10554-015-0703-1. Epub 2015 Jul 18.
  11. Vriesendorp P.A., Schinkel A.F., Soliman O.I., Kofflard M.J., de Jong P.L., van Herwerden L.A., Ten Cate F.J., Michels M.. Long-term benefit of myectomy and anterior mitral leaflet extension in obstructive hypertrophic cardiomyopathy. Am J Cardiol. 2015 Mar 1;115(5):670-5. doi:
  12. Quantitative assessment of the entire right ventricle from one acoustic window: an attractive approach. McGhie JS, Menting ME, Vletter WB, Frowijn R, Roos-Hesselink JW, van der Zwaan HB, Soliman OI, Geleijnse ML, van den Bosch AE. Eur Heart J Cardiovasc Imaging. 2016 Aug 7. pii: jew165. [Epub ahead of print]  
  13. A granular approach to improve reproducibility of the echocardiographic assessment of paravalvular regurgitation after TAVI. Abdelghani M, Ren B, Spitzer E, Tateishi H, Jonker H, Geleijnse ML, Tijssen JG, de Winter RJ, Serruys PW, Soliman OI. Int J Cardiovasc Imaging. 2016 Jul 27. [Epub ahead of print] 
  14. Echocardiographic and angiographic assessment of paravalvular regurgitation after TAVI: optimizing inter-technique reproducibility.Abdelghani M, Tateishi H, Spitzer E, Tijssen JG, de Winter RJ, Soliman OI, Hahn RT, Serruys PW. Eur Heart J Cardiovasc Imaging. 2016 Aug;17(8):852-60. doi: 10.1093/ehjci/jew083. Epub 2016 May 25.

Cardiac Computed Tomography

  1. Nieman K, Oudkerk M, Rensing BJ, van Ooijen P, Munne A, van Geuns RJ, de Feyter PJ. Coronary angiography with multi-slice computed tomography. Lancet. 2001;357:599-603.
  2. Meijboom WB, Meijs MF, Schuijf JD, Cramer MJ, Mollet NR, van Mieghem CA, Nieman K, van Werkhoven JM, Pundziute G, Weustink AC, de Vos AM, Pugliese F, Rensing B, Jukema JW, Bax JJ, Prokop M, Doevendans PA, Hunink MG, Krestin GP, de Feyter PJ. Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol. 2008;52:2135-44.
  3. Papadopoulou SL, Neefjes LA, Schaap M, Li HL, Capuano E, van der Giessen AG, Schuurbiers JC, Gijsen FJ, Dharampal AS, Nieman K, van Geuns RJ, Mollet NR, de Feyter PJ. Detection and quantification of coronary atherosclerotic plaque by 64-slice multidetector CT: a systematic head-to-head comparison with intravascular ultrasound. Atherosclerosis. 2011;219:163-70.
  4. Van Mieghem CA, Cademartiri F, Mollet NR, Malagutti P, Valgimigli M, Meijboom WB, Pugliese F, McFadden EP, Ligthart J, Runza G, Bruining N, Smits PC, Regar E, van der Giessen WJ, Sianos G, van Domburg R, de Jaegere P, Krestin GP, Serruys PW, de Feyter PJ. Multislice spiral computed tomography for the evaluation of stent patency after left main coronary artery stenting: a comparison with conventional coronary angiography and intravascular ultrasound. Circulation. 2006;114:645-53.
  5. Malagutti P, Nieman K, Meijboom WB, van Mieghem CA, Pugliese F, Cademartiri F, Mollet NR, Boersma E, de Jaegere PP, de Feyter PJ. Use of 64-slice CT in symptomatic patients after coronary bypass surgery: evaluation of grafts and coronary arteries. Eur Heart J. 2007;28:1879-85.
  6. Nieman K, Shapiro MD, Ferencik M, Nomura CH, Abbara S, Hoffmann U, Gold HK, Jang IK, Brady TJ, Cury RC. Reperfused myocardial infarction: contrast-enhanced 64-Section CT in comparison to MR imaging. Radiology. 2008;247:49-56.
  7. Sarwar A, Shapiro MD, Nasir K, Nieman K, Nomura CH, Brady TJ, Cury RC. Evaluating global and regional left ventricular function in patients with reperfused acute myocardial infarction by 64-slice multidetector CT: a comparison to magnetic resonance imaging. J Cardiovasc Comput Tomogr. 2009;3:170-7.
  8. Rossi A, Uitterdijk A, Dijkshoorn M, Klotz E, Dharampal A, van Straten M, van der Giessen WJ, Mollet N, van Geuns RJ, Krestin GP, Duncker DJ, de Feyter PJ, Merkus D. Quantification of myocardial blood flow by adenosine-stress CT perfusion imaging in pigs during various degrees of stenosis correlates well with coronary artery blood flow and fractional flow reserve. Eur Heart J Cardiovasc Imaging. 
  9. Schultz CJ, Weustink A, Piazza N, Otten A, Mollet N, Krestin G, van Geuns RJ, de Feyter P, Serruys PW, de Jaegere P. Geometry and degree of apposition of the CoreValve ReValving system with multislice computed tomography after implantation in patients with aortic stenosis. J Am Coll Cardiol. 2009;54:911-8.
  10. Serruys PW, Ormiston JA, Onuma Y, Regar E, Gonzalo N, Garcia-Garcia HM, Nieman K, Bruining N, Dorange C, Miquel-Hébert K, Veldhof S, Webster M, Thuesen L, Dudek D. A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods. Lancet. 2009;373:897-910. 
  11. A simplified and reproducible method to size the mitral annulus: implications for transcatheter mitral valve replacement. Abdelghani M, Spitzer E, Soliman OI, Beitzke D, Laggner R, Cavalcante R, Tateishi H, Campos CM, Verstraeten L, Sotomi Y, Tenekecioglu E, Onuma Y, Tijssen JG, de Winter RJ, Maisano F, Serruys PW. Eur Heart J Cardiovasc Imaging. 2016 Jun 26. pii: jew132. [Epub ahead of print] 

Structural Heart 

  1. Soliman OI, El Faquir N, Ren B, Spitzer E, van Gils L, Jonker H, Geleijnse ML,van Es GA, Tijssen JG, van Mieghem NM, de Jaegere PP. Comparison of valveperformance of the mechanically expanding Lotus and the balloon-expanded SAPIEN3 transcatheter heart valves: an observational study with independent corelaboratory analysis. Eur Heart J Cardiovasc Imaging. 2017 Jan 6. pii: jew280.doi: 10.1093/ehjci/jew280. [Epub ahead of print] PubMed PMID: 28064153. 
  2. Abdelghani M, Tateishi H, Miyazaki Y, Cavalcante R, Soliman OI, Tijssen JG, deWinter RJ, Baan J Jr, Onuma Y, Campos CM, Leite RS, Mangione JA, Abizaid A, LemosPA, de Brito FS Jr, Serruys PW. Angiographic assessment of aortic regurgitationby video-densitometry in the setting of TAVI: Echocardiographic and clinicalcorrelates. Catheter Cardiovasc Interv. 2017 Jan 21. doi: 10.1002/ccd.26926.[Epub ahead of print] PubMed PMID: 28109043.
  3. Tateishi H, Abdelghani M, Cavalcante R, Miyazaki Y, Campos CM, Collet C, SlotsTL, Leite RS, Mangione JA, Abizaid A, Soliman OI, Spitzer E, Onuma Y, Serruys PW,Lemos PA, de Brito FS Jr. The interaction of de-novo and pre-existing aorticregurgitation after TAVI: Insights from a new quantitative aortographictechnique. EuroIntervention. 2016 Dec 20. pii: EIJ-D-16-00647. doi:10.4244/EIJ-D-16-00647. [Epub ahead of print] PubMed PMID: 27993754.  
  4. M Di Martino LF, I Soliman OI, Vletter WB, Ren B, de Vries T, Galema TW, VanMieghem NM, de Jaegere PP, Geleijnse ML. Quantitative Doppler for Estimation ofParavalvular Leakage after Transcatheter Aortic Valve Implantation. J Heart ValveDis. 2016 May;25(3):289-295. PubMed PMID: 27989038.  
  5. Geleijnse ML, Di Martino LF, Vletter WB, Ren B, Galema TW, Van Mieghem NM, de Jaegere PP, Soliman OI. Limitations and difficulties of echocardiographicshort-axis assessment of paravalvular leakage after corevalve transcatheteraortic valve implantation. Cardiovasc Ultrasound. 2016 Sep 6;14(1):37. doi:10.1186/s12947-016-0080-5. Review. PubMed PMID: 27600600; PubMed Central PMCID:PMC5011797.